Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31466437 | 0.89 | DRD2 (0.47) | DRD2DRD3MAPTALOX15HTR2A | |
| SCHEMBL31466156 | 0.82 | HTR4 (0.42) | DRD2DRD3DRD4SMN1; SMN2RAB9A | |
| SCHEMBL31465999 | 0.73 | SIGMAR1 (0.54) | KDM4ESIGMAR1 | |
| SCHEMBL31466529 | 0.73 | SIGMAR1 (0.67) | SIGMAR1 | |
| SCHEMBL31466378 | 0.72 | KHK (0.56) | MAPTALOX15HTR1AHTR7SIGMAR1 | |
| SCHEMBL31465866 | 0.72 | SIGMAR1 (0.52) | DRD2HTR7SIGMAR1SMN1; SMN2SMO | |
| SCHEMBL31465845 | 0.71 | DRD2 (0.50) | DRD2HTR1AHTR2AHTR7KDM4E | |
| SCHEMBL31466526 | 0.71 | DRD2 (0.40) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL11084741 | 0.71 | DRD2 (0.67) | DRD2DRD3DRD4HTR1AKDM4E | |
| SCHEMBL31466412 | 0.70 | KDM4E (0.46) | DRD2DRD4KDM4ESIGMAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |