Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31465843 | 0.90 | SIGMAR1 (0.47) | SIGMAR1SMN1; SMN2NPC1LMNATP53 | |
| SCHEMBL31466156 | 0.89 | HTR4 (0.42) | DRD2DRD3SMN1; SMN2NPC1LMNA | |
| SCHEMBL31466437 | 0.83 | DRD2 (0.47) | DRD2DRD3SIGMAR1TMEM97KCNH2 | |
| SCHEMBL31466615 | 0.79 | SIGMAR1 (0.45) | SIGMAR1SMN1; SMN2HTR2BKCNH2 | |
| SCHEMBL31465869 | 0.79 | SIGMAR1 (0.52) | DRD2SIGMAR1HTR2BKCNH2ACHE | |
| SCHEMBL31466107 | 0.78 | SIGMAR1 (0.44) | DRD2SIGMAR1HTR2BKCNH2 | |
| SCHEMBL31465985 | 0.76 | ABL1 (0.46) | DRD2SIGMAR1HTR2BHTR1ADRD4 | |
| SCHEMBL31465980 | 0.74 | SIGMAR1 (0.44) | SIGMAR1HTR2BKCNH2 | |
| SCHEMBL31466142 | 0.71 | DRD2 (0.43) | DRD2DRD3SIGMAR1SMN1; SMN2RAB9A | |
| SCHEMBL14686768 | 0.71 | PRCP (0.57) | DRD2DRD3SIGMAR1DRD4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |