Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174608 | 0.82 | LMNA (0.70) | LMNAPTGS1PTGS2MEN1KMT2A | |
| SCHEMBL31465922 | 0.81 | MAPT (0.45) | MAPTKDM4EALDH1A1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL11382992 | 0.81 | LMNA (0.68) | LMNAPTGS1PTGS2MEN1KMT2A | |
| SCHEMBL23401297 | 0.79 | LMNA (0.53) | LMNAPTGS1PTGS2MEN1KMT2A | |
| SCHEMBL31466262 | 0.79 | POLB (0.47) | LMNAPTGS1PTGS2MEN1KMT2A | |
| SCHEMBL14996582 | 0.78 | MAPK1 (0.51) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL15887795 | 0.77 | MAPK14 (0.52) | LMNAPTGS1PTGS2MEN1KMT2A | |
| SCHEMBL27420552 | 0.77 | LMNA (0.50) | LMNAPTGS1PTGS2MEN1KMT2A | |
| SCHEMBL25290446 | 0.76 | ALDH1A1 (0.53) | LMNAPTGS1MEN1KMT2ATSHR | |
| SCHEMBL6172133 | 0.76 | PTGS2 (0.69) | LMNAPTGS1PTGS2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |