Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14996582 | 0.81 | MAPK1 (0.51) | NPC1SMN1; SMN2GAARAB9ARIPK1 | |
| SCHEMBL12770967 | 0.81 | POLB (0.64) | POLBNPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31466243 | 0.79 | LMNA (0.53) | POLBNPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19086917 | 0.78 | POLB (0.47) | POLBNPC1MEN1KMT2AATM | |
| SCHEMBL14996548 | 0.77 | LMNA (0.48) | LMNAL3MBTL1 | |
| SCHEMBL18865774 | 0.77 | SLC34A1 (0.43) | RIPK1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL14314274 | 0.75 | PRKCZ (0.55) | POLBPTGS2PTGS1 | |
| SCHEMBL31465922 | 0.74 | MAPT (0.45) | POLBSMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL25290446 | 0.73 | ALDH1A1 (0.53) | POLBMEN1KMT2AGAARAB9A | |
| SCHEMBL2865749 | 0.73 | SMN1; SMN2 (0.66) | MEN1KMT2AATMSMN1; SMN2PPP1CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |