Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP4 | P49662 | 1/20 | 0.46 |
| ▸ | CASP5 | P51878 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | BPTF | Q12830 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269262 | 0.84 | KDM4E (0.50) | CASP1CASP4CASP5HRH4PDE10A | |
| SCHEMBL14822948 | 0.79 | KMT2A (0.49) | HRH4JAK2AURKAALDH1A1 | |
| SCHEMBL31466460 | 0.73 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL31466248 | 0.73 | RET (0.43) | HRH4AURKA | |
| SCHEMBL16178307 | 0.71 | ADRB1 (0.43) | CASP1CASP4CASP5HRH4ADRB1 | |
| SCHEMBL30883037 | 0.71 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1PDE10AALDH1A1 | |
| SCHEMBL30877258 | 0.69 | L3MBTL1 (0.39) | PDE10ACYP1A2AURKAALDH1A1 | |
| SCHEMBL14538234 | 0.68 | CYP1A2 (0.57) | CASP1CASP4CASP5HRH4ADRB1 | |
| SCHEMBL945117 | 0.68 | CASP1 (0.53) | CASP1CASP4CASP5HRH4ADRB1 | |
| SCHEMBL3635646 | 0.68 | BPTF (0.47) | CASP1CASP4CASP5ADRB1PLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |