SCHEMBL3146912

SCHEMBL3146912

CC1(C)CCCC2(C)C(=O)CCCC12

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 11/20 0.44
ALOX5 P09917 1/20 0.40
ALOX15 P16050 1/20 0.40
ALOX12 P18054 1/20 0.40
CYP3A4 P08684 3/20 0.38
USP2 O75604 2/20 0.38
TP53 P04637 2/20 0.38
HSP90AA1 P07900 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 2/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
CETP P11597 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL266913 1.00 CYP19A1 (0.44) CYP19A1ALOX5ALOX15ALOX12CYP3A4
SCHEMBL21917264 0.90 CYP19A1 (0.49) CYP19A1ALOX5ALOX15ALOX12CYP3A4
SCHEMBL14880005 0.90 CYP19A1 (0.49) CYP19A1ALOX5ALOX15ALOX12CYP3A4
SCHEMBL279978 0.74 SOD1 (0.54) ALOX15CYP3A4USP2TP53HSP90AA1
SCHEMBL280128 0.74 SOD1 (0.54) ALOX15CYP3A4USP2TP53HSP90AA1
SCHEMBL3146702 0.72 PIK3CA (0.42) CYP19A1ALOX5ALOX15ALOX12CYP3A4
SCHEMBL11800559 0.69 CYP19A1 (0.46) CYP19A1MEN1MAPTKMT2ATSHR
SCHEMBL25435184 0.69 CYP19A1 (0.48) CYP19A1ALOX5ALOX15ALOX12CYP3A4
SCHEMBL25436089 0.69 CYP19A1 (0.48) CYP19A1ALOX5ALOX15ALOX12CYP3A4
SCHEMBL25432736 0.69 CYP19A1 (0.48) CYP19A1ALOX5ALOX15ALOX12CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116807912-A Use of volatile components to limit or eliminate perception of malodor 弗门尼舍有限公司 2023-09-29 CN claimed
US-20230233425-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR FIRMENICH SA (CH) 2023-07-27 US claimed
US-20200345601-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR FIRMENICH SA (CH) 2020-11-05 US claimed
EP-3713610-A2 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR Firmenich SA (CH) 2020-09-30 EP claimed
CN-111432851-A Use of volatile ingredients to limit or eliminate perception of malodour 弗门尼舍有限公司 2020-07-17 CN claimed
WO-2019101821-A2 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR FIRMENICH SA (CH) 2019-05-31 WO claimed
EP-4632382-A2 METHOD OF IDENTIFYING LAUNDRY MALODOR, MOLDY MALODOR AND/OR SWEAT MALODOR MODULATING COMPOUNDS Firmenich SA (CH) 2025-10-15 EP disclosed
CN-116807912-A Use of volatile components to limit or eliminate perception of malodor 弗门尼舍有限公司 2023-09-29 CN disclosed
US-11744785-B2 Use of volatile compositions to limit or eliminate the perception of malodor FIRMENICH SA (CH) 2023-09-05 US disclosed
US-20230233425-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR FIRMENICH SA (CH) 2023-07-27 US disclosed
CN-111432851-B Use of volatile components to limit or eliminate perception of malodor 弗门尼舍有限公司 2023-06-23 CN disclosed
US-20200345601-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR FIRMENICH SA (CH) 2020-11-05 US disclosed
EP-3713610-A2 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR Firmenich SA (CH) 2020-09-30 EP disclosed
CN-111432851-A Use of volatile ingredients to limit or eliminate perception of malodour 弗门尼舍有限公司 2020-07-17 CN disclosed
WO-2019101821-A2 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR FIRMENICH SA (CH) 2019-05-31 WO disclosed
EP-1910262-B1 NAPHTHALENONE DERIVATIVE WITH POWDERY-IONONE TYPE ODOURS FIRMENICH & CIE (CH) 2010-03-03 EP disclosed
US-20080214419-A1 Naphthalenone Derivative with Powdery-Ionone Type Odors FIRMENICH SA (CH) 2008-09-04 US disclosed
EP-1910262-A1 NAPHTHALENONE DERIVATIVE WITH POWDERY-IONONE TYPE ODOURS FIRMENICH SA (CH) 2008-04-16 EP disclosed
WO-2007010420-A1 NAPHTHALENONE DERIVATIVE WITH POWDERY-IONONE TYPE ODOURS FIRMENICH SA (CH) 2007-01-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11744785-B2 Use of volatile compositions to limit or eliminate the perception of malodor TAS2R8, TRPA1, TAS2R10 CYP19A1 2700/4885ALOX5 199/4885ALOX15 514/4885
US-20080214419-A1 Naphthalenone Derivative with Powdery-Ionone Type Odors IPO5, TRPA1, SCN5A CYP19A1 799/4885ALOX5 610/4885ALOX15 1144/4885
US-20200345601-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR TAS2R8, TRPA1, TAS2R10 CYP19A1 2700/4885ALOX5 199/4885ALOX15 514/4885
US-20230233425-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR TAS2R8, TRPA1, TAS2R10 CYP19A1 2700/4885ALOX5 199/4885ALOX15 514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.