Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PARG | Q86W56 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | BRS3 | P32247 | 4/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31467646 | 0.82 | KMT2A (0.45) | TRPV4PTGS2MAPTUSP2POLB | |
| SCHEMBL31467645 | 0.82 | KMT2A (0.45) | TRPV4PTGS2MAPTUSP2POLB | |
| SCHEMBL31467610 | 0.82 | ALDH1A1 (0.46) | TRPV4PTGS2POLB | |
| SCHEMBL25371906 | 0.82 | TRPV4 (0.44) | TRPV4BRS3POLBCYP2D6NR1I2 | |
| SCHEMBL30567044 | 0.82 | TRPV4 (0.44) | TRPV4BRS3POLBCYP2D6NR1I2 | |
| SCHEMBL31467612 | 0.82 | TRPV4 (0.39) | TRPV4BRS3RORCCYP2D6NR1I2 | |
| SCHEMBL31467641 | 0.81 | TRPV4 (0.41) | TRPV4BRS3USP2CYP3A4RORC | |
| SCHEMBL31467643 | 0.81 | CYP3A4 (0.47) | TRPV4USP2CYP3A4TP53POLB | |
| SCHEMBL31467620 | 0.80 | TRPV4 (0.41) | TLR7TRPV4USP2CYP3A4RORC | |
| SCHEMBL31467598 | 0.80 | TRPV4 (0.41) | TRPV4BRS3USP2CYP3A4RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049275-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2025-03-06 | — | — | WO | disclosed |