Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31467646 | 1.00 | KMT2A (0.45) | KMT2ATRPV4ALDH1A1KDM4ENPSR1 | |
| SCHEMBL31467636 | 0.82 | TLR7 (0.40) | TRPV4USP2MAPTPTGS2POLB | |
| SCHEMBL25371906 | 0.82 | TRPV4 (0.44) | TRPV4ALDH1A1KDM4EPOLB | |
| SCHEMBL30567044 | 0.82 | TRPV4 (0.44) | TRPV4ALDH1A1KDM4EPOLB | |
| SCHEMBL31467612 | 0.82 | TRPV4 (0.39) | TRPV4KDM4E | |
| SCHEMBL31467629 | 0.81 | TRPV4 (0.40) | KMT2ATRPV4KDM4EUSP2MAPT | |
| SCHEMBL31467641 | 0.81 | TRPV4 (0.41) | TRPV4ALDH1A1USP2 | |
| SCHEMBL31467643 | 0.81 | CYP3A4 (0.47) | KMT2ATRPV4ALDH1A1KDM4EMEN1 | |
| SCHEMBL31467610 | 0.80 | ALDH1A1 (0.46) | KMT2ATRPV4ALDH1A1KDM4ENPSR1 | |
| SCHEMBL25371347 | 0.80 | TRPV4 (0.41) | TRPV4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049275-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2025-03-06 | — | — | WO | disclosed |