Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107103 | 0.81 | CYP1A2 (0.43) | PARP1PARP10HTR5ACHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL1266812 | 0.79 | CYP1A2 (0.42) | PARP1PARP10HTR5ACHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL2315581 | 0.77 | CYP1A2 (0.41) | PARP1PARP10HTR5ACHRNB2CHRNB4 | |
| SCHEMBL30487334 | 0.71 | HTR2C (0.32) | PARP1PARP10HTR2C | |
| SCHEMBL31020116 | 0.71 | ASIC3 (0.39) | PARP1PARP10HTR5ACHRNB2CHRNB4 | |
| SCHEMBL330372 | 0.70 | ASIC3 (0.60) | HTR2AHTR2CADRA2AADRA2BADRA2C | |
| SCHEMBL29741628 | 0.70 | PNMT (0.60) | HTR2AHTR2CADRA2AADRA2BADRA2C | |
| SCHEMBL420370 | 0.70 | PNMT (0.60) | HTR2AHTR2CADRA2AADRA2BADRA2C | |
| SCHEMBL29379063 | 0.69 | — | — | |
| SCHEMBL31441326 | 0.69 | PARP1 (0.41) | PARP1PARP10CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025029683-A1 | PI3K INHIBITORS | COGENT BIOSCIENCES, INC. (US) | 2025-02-06 | — | — | WO | disclosed |