SCHEMBL30487334

SCHEMBL30487334

[2H]N1CC=Cc2cc(F)ccc2C1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.32
PARP1 P09874 1/20 0.30
PARP10 Q53GL7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25292571 0.82 HTR2C (0.33) HTR2CPARP1PARP10
SCHEMBL30487438 0.82 HTR2C (0.33) HTR2CPARP1PARP10
SCHEMBL819543 0.71 ADRA2A (0.33) HTR2CPARP1PARP10
SCHEMBL17068939 0.71 ADRA2A (0.33) HTR2CPARP1PARP10
SCHEMBL31468751 0.71 PARP1 (0.36) HTR2CPARP1PARP10
SCHEMBL30344009 0.68 KDM1A (0.37) HTR2CPARP1PARP10
SCHEMBL30695309 0.67 HTR5A (0.33) HTR2CPARP1PARP10
SCHEMBL30688503 0.63 TNKS2 (0.36) HTR2CPARP1PARP10
SCHEMBL15351980 0.61 ACHE (0.34) HTR2CPARP1PARP10
SCHEMBL563934 0.59 TRPA1 (0.37) HTR2CPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125935-A1 BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2023-07-06 WO disclosed