SCHEMBL3146879

SCHEMBL3146879

CCCCC(Cc1ccc(O)c(OC)c1)OC(CCCC)Cc1ccc(O)c(OC)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOS P01100 1/20 0.60
TTR P02766 1/20 0.60
JUN P05412 1/20 0.60
NR3C1 P04150 1/20 0.60
HSD17B1 P14061 1/20 0.60
HSD17B2 P37059 1/20 0.60
HTR1A P08908 3/20 0.58
CYP3A4 P08684 5/20 0.57
MMP1 P03956 1/20 0.57
ALOX15 P16050 1/20 0.56
ALOX12 P18054 1/20 0.56
CYP2C8 P10632 4/20 0.51
CYP2C9 P11712 4/20 0.51
CYP2B6 P20813 4/20 0.51
CYP2C19 P33261 4/20 0.51
CYP1A2 P05177 3/20 0.51
LTA4H P09960 2/20 0.51
TRPV1 Q8NER1 1/20 0.51
CYP2D6 P10635 2/20 0.50
CYP2A6 P11509 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3157908 0.97 HTR1A (0.62) FOSTTRJUNNR3C1HSD17B1
SCHEMBL676400 0.93 FOS (0.62) FOSTTRJUNNR3C1HSD17B1
SCHEMBL3158709 0.86 FOS (0.66) FOSTTRJUNNR3C1HSD17B1
Acetic Acid SCHEMBL3241741 0.86 FOS (0.55) FOSTTRJUNNR3C1HSD17B1
SCHEMBL21402294 0.86 ALOX15 (0.57) HTR1ACYP3A4ALOX15ALOX12CYP2C8
SCHEMBL3241738 0.81 LTA4H (0.49) FOSTTRJUNNR3C1HSD17B1
SCHEMBL21402299 0.81 ALOX15 (0.62) FOSTTRJUNNR3C1HSD17B1
SCHEMBL15259679 0.80 FOS (0.54) FOSTTRJUNNR3C1HSD17B1
SCHEMBL28377905 0.79 FOS (0.56) FOSTTRJUNNR3C1HSD17B1
SCHEMBL31710801 0.78 TAAR1 (0.69) HTR1ACYP3A4CYP2C8CYP2C9CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3453364-B1 HEAT GENERATOR KOBAYASHI PHARMACEUTICAL CO LTD (JP) 2022-08-24 EP claimed
EP-3348242-B1 HEATING COMPRESS KOBAYASHI PHARMACEUTICAL CO LTD (JP) 2022-06-29 EP claimed
EP-2810564-B1 Sensation masking composition TAKASAGO INT CORP (USA) (US) 2017-06-14 EP claimed
EP-1912516-B1 SENSATION MASKING COMPOSITION TAKASAGO INTERNAT CORP USA (US) 2014-06-25 EP claimed
EP-1215258-B1 Flavor composition for food and drink or for oral care preparation TAKASAGO PERFUMERY CO LTD (JP) 2010-02-17 EP claimed
EP-1215257-B1 Fragance composition TAKASAGO PERFUMERY CO LTD (JP) 2009-10-21 EP claimed
US-20150246131-A1 WATER-BASED PERSONAL LUBRICANTS WITH A SILICONE COMPONENT CHURCH & DWIGHT, CO., INC. (US) 2015-09-03 US disclosed