Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CTSA | P10619 | 8/20 | 0.47 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17260080 | 1.00 | ALDH1A1 (0.66) | ALDH1A1MAPTKDM4ESMN1; SMN2NOX4 | |
| SCHEMBL5527948 | 0.82 | MAPT (0.70) | ALDH1A1MAPTKDM4ESMN1; SMN2NOX4 | |
| SCHEMBL20268413 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4ESMN1; SMN2NOX4 | |
| SCHEMBL4029048 | 0.79 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4ESMN1; SMN2NOX4 | |
| SCHEMBL9765242 | 0.79 | MAPT (0.66) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL9455149 | 0.79 | ALDH1A1 (0.66) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL10743336 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4ESMN1; SMN2NOX4 | |
| SCHEMBL1564411 | 0.77 | MAPT (0.62) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL5528033 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4ESMN1; SMN2NOX4 | |
| SCHEMBL11435207 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029158-A | EGFR inhibitors | 缆图药品公司 | 2026-05-12 | — | — | CN | disclosed |
| WO-2025080784-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-04-17 | — | — | WO | disclosed |