Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 3/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.40 |
| ▸ | XIAP | P98170 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5527948 | 0.82 | MAPT (0.70) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL4029048 | 0.79 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL9765242 | 0.79 | MAPT (0.66) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL17260080 | 0.79 | ALDH1A1 (0.66) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL31469255 | 0.79 | ALDH1A1 (0.66) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL5528033 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL1564411 | 0.77 | MAPT (0.62) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL9558930 | 0.76 | ALKBH5 (0.51) | — | |
| SCHEMBL11435207 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL1819741 | 0.76 | MAPT (0.60) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5274083-A | A 2-halopyrimidinylaminoalkylamino-4-chloro-6-sulfonyl-substituted chromophore group-s-triazine | BAYER AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |
| US-4225492-A | Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |