SCHEMBL5528033

SCHEMBL5528033

COc1ccccc1-n1[nH]c(C)cc1=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.62
MAPT P10636 7/20 0.62
KDM4E B2RXH2 5/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
HTT P42858 3/20 0.54
GAA P10253 2/20 0.54
LMNA P02545 2/20 0.54
RECQL P46063 1/20 0.54
MGLL Q99685 1/20 0.47
KMT2A Q03164 4/20 0.46
MEN1 O00255 2/20 0.45
ALKBH3 Q96Q83 1/20 0.44
HPGD P15428 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
ADRB1 P08588 1/20 0.41
DRD2 P14416 1/20 0.41
CYP2C19 P33261 1/20 0.41
DRD3 P35462 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9765224 0.83 ALDH1A1 (0.53) ALDH1A1MAPTKDM4ESMN1; SMN2HTT
SCHEMBL5527948 0.80 MAPT (0.70) ALDH1A1MAPTKDM4ESMN1; SMN2HTT
SCHEMBL10940578 0.79 ALKBH5 (0.59) ALDH1A1KDM4EMGLLKMT2AMEN1
SCHEMBL31469255 0.77 ALDH1A1 (0.66) ALDH1A1MAPTKDM4ESMN1; SMN2HTT
SCHEMBL9765242 0.77 MAPT (0.66) ALDH1A1MAPTKDM4ESMN1; SMN2HTT
SCHEMBL4029048 0.77 ALDH1A1 (1.00) ALDH1A1MAPTKDM4ESMN1; SMN2HTT
SCHEMBL9455149 0.77 ALDH1A1 (0.66) ALDH1A1MAPTKDM4ESMN1; SMN2HTT
SCHEMBL17260080 0.77 ALDH1A1 (0.66) ALDH1A1MAPTKDM4ESMN1; SMN2HTT
SCHEMBL11534123 0.75 TSHR (0.42) ALDH1A1MAPTKDM4EHTTRECQL
SCHEMBL1564411 0.74 MAPT (0.62) ALDH1A1MAPTKDM4ESMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070269641-A1 Solvent Stable Tinted Iridescent Film GRANEY DANIEL J 2007-11-22 US disclosed
EP-1656252-A1 SOLVENT STABLE TINTED IRIDESCENT FILM Engelhard Corporation (US) 2006-05-17 EP disclosed
WO-2005018931-A1 SOLVENT STABLE TINTED IRIDESCENT FILM ENGELHARD CORPORATION (US) 2005-03-03 WO disclosed
EP-0914386-B1 PIGMENT COMPOSITIONS ENGELHARD CORP (US) 2002-03-27 EP disclosed
EP-0914386-A1 PIGMENT COMPOSITIONS Engelhard Corporation (US) 1999-05-12 EP disclosed
WO-1997045493-A1 PIGMENT COMPOSITIONS ENGELHARD CORPORATION (US) 1997-12-04 WO disclosed
US-5669967-A MONOAZO DYES, PYRAZOLE DYES FOR INKS, PAINTS AND PLASTICS ENGELHARD CORPORATION (US) 1997-09-23 US disclosed
US-5204453-A Process for the preparation of 1:2 metal complex azo compounds by carrying out diazotization and coupling in the presence of a metal donor CIBA-GEIGY CORPORATION (US) 1993-04-20 US disclosed
EP-0241414-B1 PROCESS FOR THE PREPARATION OF 1:2 METAL COMPLEX AZO DYES CIBA-GEIGY AG (CH) 1991-05-08 EP disclosed
US-5001227-A Fibre-reactive 1:1 chromium complex azo or azomethine dyes having a bidentate chelating group and a monofunctional neutral ligand CIBA-GEIGY CORPORATION (US) 1991-03-19 US disclosed
US-4436659-A DYEING POLYAMIDS, AZO DYES CIBA-GEIGY CORPORATION (US) 1984-03-13 US disclosed
EP-0063261-A2 Cationic azo dyestuffs, their preparation and their use BAYER AG (DE) 1982-10-27 EP disclosed
US-4318849-A COPPER, NICKEL, CHROMIUM OR COBALT COMPLEXES OF AZO OR AZO-METHINE DYES CIBA-GEIGY CORPORATION (US) 1982-03-09 US disclosed
US-4215042-A PRINTING AND DYEING OF POLYAMIDES; COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1980-07-29 US disclosed
US-RE29585-E DYEING WOOL CIBA-GEIGY CORPORATION (US) 1978-03-21 US disclosed
US-4075198-A PROCESS FOR MANUFACTURE OF BENZIDINE PIGMENTS COLOUR-CHEM LTD. (IN) 1978-02-21 US disclosed
US-3978037-A POLYAMIDES CIBA-GEIGY CORPORATION (US) 1976-08-31 US disclosed
US-3971741-A DISPERSION PIGMENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US disclosed