SCHEMBL9765242

SCHEMBL9765242

CCc1ccccc1-n1[nH]c(C)cc1=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.66
ALDH1A1 P00352 6/20 0.66
KDM4E B2RXH2 5/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
KMT2A Q03164 6/20 0.48
MEN1 O00255 3/20 0.47
GAA P10253 2/20 0.47
HTT P42858 2/20 0.47
ALKBH3 Q96Q83 1/20 0.47
LMNA P02545 3/20 0.45
RECQL P46063 1/20 0.45
MGLL Q99685 1/20 0.44
TDP1 Q9NUW8 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.42
TSHR P16473 1/20 0.41
ALPL P05186 1/20 0.41
POLB P06746 1/20 0.40
ALOX5 P09917 1/20 0.40
KDM5A P29375 1/20 0.39
KDM2B Q8NHM5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3316826 0.85 ALDH1A1 (0.54) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL5527948 0.82 MAPT (0.70) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL4029048 0.79 ALDH1A1 (1.00) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL17260080 0.79 ALDH1A1 (0.66) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL31469255 0.79 ALDH1A1 (0.66) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL9455149 0.79 ALDH1A1 (0.66) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL10359609 0.79 ALDH1A1 (0.45) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL10877086 0.78 MAPT (0.46) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL9548226 0.78 ALKBH5 (0.54) ALDH1A1KDM4E
SCHEMBL5528033 0.77 ALDH1A1 (0.62) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0260557-B1 ASYMMETRIC 1:2 METAL COMPLEX DYESTUFS BAYER AG (DE) 1991-11-27 EP disclosed
EP-0260562-B1 ASYMMETRIC 1:2 CHROMIUM COMPLEX DYESTUFFS BAYER AG (DE) 1991-08-07 EP disclosed
US-4997917-A Preparation of 1:2 chromium complex azo dyes asymmetrically substituted with solubilizing CIBA-GEIGY CORPORATION (US) 1991-03-05 US disclosed
EP-0260557-A2 Asymmetric 1:2 metal complex dyestufs BAYER AG (DE) 1988-03-23 EP disclosed
EP-0260562-A2 Asymmetric 1:2 chromium complex dyestuffs BAYER AG (DE) 1988-03-23 EP disclosed
EP-0072501-B1 ASYMMETRIC 1:2 CHROMIUM-COMPLEX DYESTUFFS BAYER AG (DE) 1986-12-03 EP disclosed
EP-0072515-B1 PESTICIDE, ITS PREPARATION AND USE BAYER AG (DE) 1986-08-13 EP disclosed
US-4567139-A ENZYMATIC REACTIONS; MEDICAL DIAGNOSIS BOEHRINGER MANNHEIM GMBH (DE) 1986-01-28 US disclosed
US-4394512-A CHROMOGENS FOR MEASURING HYDROGEN PEROXIDE FORMATION IN ENZYMATI-C REACTION BOEHRINGER MANNHEIM GMBH (DE) 1983-07-19 US disclosed
EP-0012716-B1 MONOCHLOROTRIAZINE DYESTUFFS OF THE PYRAZOLONE SERIES, THEIR PREPARATION AND THEIR USE FOR DYEING AND PRINTING TEXTILE MATERIALS CIBA-GEIGY AG (CH) 1983-06-15 EP disclosed
EP-0072516-A1 Chromium-complex dyestuffs BAYER AG (DE) 1983-02-23 EP disclosed
EP-0033539-B1 USE OF AMINOANTIPYRINE COMPOUNDS AND NEW AMINOANTIPYRINE DERIVATIVES Roche Diagnostics GmbH (DE) 1983-01-19 EP disclosed
US-4348318-A DYEING AND PRINTING TEXTILES; MONOAZO, TRIAZINE, HYDRAZONE, AND PYRAZOLONE DYES CIBA-GEIGY CORPORATION (US) 1982-09-07 US disclosed
EP-0033539-A1 Use of aminoantipyrine compounds and new aminoantipyrine derivatives Roche Diagnostics GmbH (DE) 1981-08-12 EP disclosed
US-4234479-A PRINTING AND DYEING NITROGEN-CONTAINING FIBERS; YELLOW BAYER AKTIENGESELLSCHAFT (DE) 1980-11-18 US disclosed
EP-0017768-A1 Reactive dyestuffs and their use BASF Aktiengesellschaft (DE) 1980-10-29 EP disclosed
US-4225492-A Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines CASSELLA AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
US-4083839-A Unsymmetrical mono sulfo containing 1:2 azo, azo chromium complex dyes CIBA-GEIGY CORPORATION (US) 1978-04-11 US disclosed
US-4029643-A Chromium containing azo dyes NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1977-06-14 US disclosed
US-3970615-A Unsymmetrical mono-sulfo containing chromium complexes of azo dyes CIBA-GEIGY CORPORATION (US) 1976-07-20 US disclosed