Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31469807 | 0.87 | KDM4E (0.61) | MEN1KMT2AALDH1A1USP2RAB9A | |
| SCHEMBL11638233 | 0.82 | PTK2 (0.59) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL15440489 | 0.81 | HPGD (0.53) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL5919129 | 0.81 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1USP2MAPT | |
| SCHEMBL9396580 | 0.80 | MEN1 (0.48) | MEN1KMT2AALDH1A1USP2RAB9A | |
| SCHEMBL9398335 | 0.79 | PKM (0.47) | MEN1KMT2AALDH1A1USP2RAB9A | |
| SCHEMBL6643211 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1USP2RAB9A | |
| SCHEMBL27414343 | 0.78 | MAPK8 (0.71) | RAB9ANPC1MAPTMAPK8MAPK9 | |
| SCHEMBL3798512 | 0.78 | RPS6KB1 (0.52) | MEN1KMT2AALDH1A1USP2RAB9A | |
| SCHEMBL34468523 | 0.76 | MAPT (0.52) | MEN1KMT2AALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025030002-A2 | DGK TARGETING COMPOUNDS AND USES THEREOF | ARVINAS OPERATIONS, INC. (US) | 2025-02-06 | — | — | WO | disclosed |