Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035270 | 0.79 | MAPT (0.54) | MAPTHTR1BTRPA1ATMKEAP1 | |
| SCHEMBL1538371 | 0.79 | MAPT (0.54) | MAPTHTR1BTRPA1ATMKEAP1 | |
| SCHEMBL29377898 | 0.79 | MAPT (0.54) | MAPTHTR1BTRPA1ATMKEAP1 | |
| SCHEMBL536124 | 0.79 | — | — | |
| SCHEMBL9046346 | 0.78 | CA1 (0.48) | MAPTPOLBKDM4EGAAMEN1 | |
| Formaldehyde SCHEMBL27667426 | 0.78 | MAPT (0.53) | MAPTHTR1BTRPA1ATMKEAP1 | |
| SCHEMBL29352478 | 0.77 | CA1 (0.52) | MAPTHTR1BTRPA1ATMKEAP1 | |
| SCHEMBL28575044 | 0.77 | CA1 (0.52) | MAPTHTR1BTRPA1ATMKEAP1 | |
| SCHEMBL78554 | 0.77 | CA1 (0.52) | MAPTHTR1BTRPA1ATMKEAP1 | |
| SCHEMBL6722517 | 0.77 | NCEH1 (0.33) | CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707161-A | Lightfastness of dyeings obtained with acid dyes or metal complex dyes on polyamides: treatment with copper hydroxamates | BASF AKTIENGESELLSCHAFT (DE) | 1987-11-17 | — | — | US | claimed |
| WO-2024078971-A1 | HEAT-SENSITIVE RECORDING MATERIAL | KOEHLER INNOVATION & TECHNOLOGY GMBH (DE) | 2024-04-18 | — | — | WO | disclosed |
| CN-107074878-B | 2, 3-dihydro-thiazolo [3,2-a ] pyridin-5-one derivatives, intermediates thereof and their use as antibacterial agents | 快尔生物技术公司 | 2019-12-24 | — | — | CN | disclosed |
| US-10294244-B2 | 2,3-dihydro-thiazolo[3,2-A]pyridin-5-one derivatives, intermediates thereof, and their use as antibacterial agents | QURETECH BIO AB (SE) | 2019-05-21 | — | — | US | disclosed |
| US-20170334931-A1 | 2,3-Dihydro-Thiazolo[3,2-A]Pyridin-5-One Derivatives, Intermediates Thereof, and Their Use as Antibacterial Agents | QURETECH BIO AB (SE) | 2017-11-23 | — | — | US | disclosed |
| EP-3218382-A1 | 2,3-DIHYDRO-THIAZOLO[3,2-A]PYRIDIN-5-ONE DERIVATIVES, INTERMEDIATES THEREOF, AND THEIR USE AS ANTIBACERIAL AGENTS | Quretech Bio AB (SE) | 2017-09-20 | — | — | EP | disclosed |
| WO-2016075296-A1 | 2,3-DIHYDRO-THIAZOLO[3,2-A]PYRIDIN-5-ONE DERIVATIVES, INTERMEDIATES THEREOF, AND THEIR USE AS ANTIBACERIAL AGENTS | QURETECH BIO AB (SE) | 2016-05-19 | — | — | WO | disclosed |
| US-20150224099-A1 | ANTITUBERCULOUS COMPOSITION COMPRISING OXAZOLE COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 2015-08-13 | — | — | US | disclosed |
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| US-8987304-B2 | Antituberculous composition comprising oxazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-03-24 | — | — | US | disclosed |
| US-4880718-A | AS PHOTOSENSITIZERS AND CHARGE GENERATING COMPOUNDS; OFFSET PRINTING PLATES, COPIERS, PHOTORESISTS MADE USING LASERS; HIGH CONTRAST AND VOLTAGE | BASF AKTIENGESELLSCHAFT (DE) | 1989-11-14 | — | — | US | disclosed |
| US-4789382-A | WITH DISPERSE DYES, READY EXHAUSTION, SUBLIMATION RESISTANT, BRIGHT | BASF AKTIENGESELLSCHAFT (DE) | 1988-12-06 | — | — | US | disclosed |
| EP-0254987-A2 | Benzophenone ether-esters and process for improving the light fastness of polyester colourings by the use of benzophenone ether-esters | BASF Aktiengesellschaft (DE) | 1988-02-03 | — | — | EP | disclosed |
| US-4707161-A | Lightfastness of dyeings obtained with acid dyes or metal complex dyes on polyamides: treatment with copper hydroxamates | BASF AKTIENGESELLSCHAFT (DE) | 1987-11-17 | — | — | US | disclosed |
| EP-0082817-B1 | COLOUR-PHOTOGRAPHIC RECORDING MATERIAL | CIBA-GEIGY AG (CH) | 1987-03-04 | — | — | EP | disclosed |
| US-4613334-A | COPPER HYDROXAMATE TREATMENT | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-23 | — | — | US | disclosed |
| US-4465687-A | ANTIARTHRITIC AGENT, ENZYME INHIBITOR | MERCK & CO., INC. (US) | 1984-08-14 | — | — | US | disclosed |
| US-4448968-A | HYDROLYSIS OF A 2-ALKOXY-1,3,4,-THIADIAZOLE USING HYDROCHLORIC ACID AND A NONAQUEOUS SOLVENT | CIBA-GEIGY CORPORATION (US) | 1984-05-15 | — | — | US | disclosed |
| EP-0017132-B1 | DYESTUFFS, THEIR PREPARATION AND UTILISATION | BASF Aktiengesellschaft (DE) | 1981-10-14 | — | — | EP | disclosed |
| EP-0017132-A1 | Dyestuffs, their preparation and utilisation | BASF Aktiengesellschaft (DE) | 1980-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10294244-B2 | 2,3-dihydro-thiazolo[3,2-A]pyridin-5-one derivatives, intermediates thereof, and their use as antibacterial agents | NOD1, MT-ND1, NDUFB7 | MAPT 1630/4885HTR1B 2160/4885TRPA1 1628/4885 |
| US-20170334931-A1 | 2,3-Dihydro-Thiazolo[3,2-A]Pyridin-5-One Derivatives, Intermediates Thereof, and Their Use as Antibacterial Agents | NOD1, MT-ND1, NDUFB7 | MAPT 1630/4885HTR1B 2160/4885TRPA1 1628/4885 |
| US-20150224099-A1 | ANTITUBERCULOUS COMPOSITION COMPRISING OXAZOLE COMPOUNDS | OXA1L, ARG1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | MAPT 1855/4885HTR1B 3817/4885TRPA1 3167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.