Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24767177 | 0.79 | KDM4E (0.43) | KDM4EHSD11B1ALDH1A1LMNAGAA | |
| SCHEMBL17080357 | 0.79 | PRKAB2 (0.47) | KDM4EHSD11B1ALDH1A1LMNAGAA | |
| SCHEMBL6880856 | 0.77 | SMPD3 (0.44) | SMPD3KDM4EALDH1A1ABL1KDR | |
| SCHEMBL4395064 | 0.75 | SMPD3 (0.52) | SMPD3KDR | |
| SCHEMBL10258993 | 0.75 | KDM4E (0.40) | KDM4EHSD11B1KCNJ5EGLN2IRAK4 | |
| SCHEMBL24508343 | 0.75 | HSD11B1 (0.52) | KDM4EHSD11B1ALDH1A1ATRIRAK4 | |
| SCHEMBL29791694 | 0.74 | ATR (0.44) | KDM4EHSD11B1ALDH1A1LMNAGAA | |
| SCHEMBL24508342 | 0.72 | HSD11B1 (0.53) | HSD11B1IRAK4 | |
| SCHEMBL29791699 | 0.72 | KCNJ5 (0.44) | KDM4EHSD11B1KCNJ5MEN1NPC1 | |
| SCHEMBL21893829 | 0.72 | SMPD3 (0.48) | SMPD3HSD11B1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122070287-A | IRAK 4-targeted degradation agent compound and application thereof | 江苏先声药业有限公司 | 2026-05-19 | — | — | CN | disclosed |
| WO-2025077891-A1 | DEGRADATION AGENT COMPOUND TARGETING IRAK4, AND USE THEREOF | 江苏先声药业有限公司 | 2025-04-17 | — | — | WO | disclosed |