Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 11/20 | 0.41 |
| ▸ | LATS1 | O95835 | 1/20 | 0.35 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 2/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3018852 | 0.88 | CRHR1 (0.38) | CRHR1LATS1LATS2HCAR3HCAR2 | |
| SCHEMBL5414343 | 0.83 | CRHR1 (0.51) | CRHR1CCR4 | |
| SCHEMBL3952919 | 0.77 | EGFR (0.49) | CRHR1 | |
| SCHEMBL18824620 | 0.75 | ADORA2A (0.37) | CCR4ADORA2A | |
| SCHEMBL31362142 | 0.75 | ADORA2A (0.37) | CCR4ADORA2A | |
| SCHEMBL4627789 | 0.74 | CRHR1 (0.38) | CRHR1 | |
| SCHEMBL4935031 | 0.72 | CRHR1 (0.41) | CRHR1LATS1LATS2 | |
| SCHEMBL21388100 | 0.71 | ADORA3 (0.35) | CCR4ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL3772683 | 0.70 | KMT2A (0.46) | CRHR1HCAR3HCAR2 | |
| SCHEMBL12531832 | 0.70 | KDM4E (0.47) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113490668-B | Compounds and compositions for the treatment of diseases associated with APJ receptor activity | 安娜普尔纳生物股份有限公司 | 2025-02-25 | — | — | CN | disclosed |