Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31471844 | 0.83 | HSD11B1 (0.61) | HSD11B1CHRNB2CHRNA4AKR1C3HTR7 | |
| SCHEMBL31471909 | 0.81 | HSD11B1 (0.57) | HSD11B1CTSGCMA1CHRNB2CHRNA4 | |
| SCHEMBL30121385 | 0.80 | HSD11B1 (0.70) | HSD11B1CHRNB2CHRNA4TSHR | |
| SCHEMBL4413069 | 0.80 | HSD11B1 (0.70) | HSD11B1CHRNB2CHRNA4TSHR | |
| SCHEMBL31471901 | 0.78 | HSD11B1 (0.61) | HSD11B1AKR1C3PKMLMNATSHR | |
| SCHEMBL10231078 | 0.78 | HSD11B1 (0.61) | HSD11B1AKR1C3PKMLMNATSHR | |
| SCHEMBL1618372 | 0.78 | HSD11B1 (0.61) | HSD11B1AKR1C3PKMLMNATSHR | |
| SCHEMBL31471833 | 0.78 | HSD11B1 (0.60) | HSD11B1AKR1C3HTR6PKMPKLR | |
| SCHEMBL13950417 | 0.78 | HSD11B1 (0.60) | HSD11B1AKR1C3HTR6PKMPKLR | |
| SCHEMBL31471904 | 0.75 | HSD11B1 (0.60) | HSD11B1CHRNB2CHRNA4LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025100889-A1 | QUINAZOLINE DERIVATIVE, SALT THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2025-05-15 | — | — | WO | disclosed |