Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 4/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31471844 | 0.84 | HSD11B1 (0.61) | HSD11B1MMP2MEN1KMT2AHTR1A | |
| SCHEMBL30121385 | 0.83 | HSD11B1 (0.70) | HSD11B1MMP2ALDH1A1KMT2ACHRNB2 | |
| SCHEMBL4413069 | 0.83 | HSD11B1 (0.70) | HSD11B1MMP2ALDH1A1KMT2ACHRNB2 | |
| SCHEMBL13950417 | 0.81 | HSD11B1 (0.60) | HSD11B1MMP2KMT2AAKR1C3HTR6 | |
| SCHEMBL31471833 | 0.81 | HSD11B1 (0.60) | HSD11B1MMP2KMT2AAKR1C3HTR6 | |
| SCHEMBL31471876 | 0.81 | HSD11B1 (0.57) | HSD11B1HTR7CTSGCMA1AKR1C3 | |
| SCHEMBL8692108 | 0.80 | HSD11B1 (0.54) | HSD11B1MEN1ALDH1A1KMT2AHTR6 | |
| SCHEMBL10231078 | 0.78 | HSD11B1 (0.61) | HSD11B1MEN1ALDH1A1KMT2AAKR1C3 | |
| SCHEMBL1618372 | 0.78 | HSD11B1 (0.61) | HSD11B1MEN1ALDH1A1KMT2AAKR1C3 | |
| SCHEMBL31471901 | 0.78 | HSD11B1 (0.61) | HSD11B1MEN1ALDH1A1KMT2AAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025100889-A1 | QUINAZOLINE DERIVATIVE, SALT THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2025-05-15 | — | — | WO | disclosed |