Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | CCR4 | P51679 | 9/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31471901 | 0.83 | HSD11B1 (0.61) | HSD11B1MEN1ALDH1A1KMT2A | |
| SCHEMBL10231078 | 0.83 | HSD11B1 (0.61) | HSD11B1MEN1ALDH1A1KMT2A | |
| SCHEMBL1618372 | 0.83 | HSD11B1 (0.61) | HSD11B1MEN1ALDH1A1KMT2A | |
| SCHEMBL31471909 | 0.80 | HSD11B1 (0.57) | HSD11B1HTR6CYP3A4MEN1ALDH1A1 | |
| SCHEMBL8696222 | 0.78 | NAMPT (0.42) | HSD11B1HTR6CCR4GHSRCYP1A2 | |
| SCHEMBL9091868 | 0.78 | HTR6 (0.41) | HSD11B1HTR6CCR4GHSRCYP1A2 | |
| SCHEMBL8691870 | 0.75 | HTR6 (0.49) | HTR6CCR4GHSRCYP1A2CYP3A4 | |
| SCHEMBL31471844 | 0.75 | HSD11B1 (0.61) | HSD11B1HTR6MEN1KMT2AALOX5AP | |
| SCHEMBL566287 | 0.74 | HSD11B1 (0.54) | HSD11B1ALOX5APFEN1CHRNB2CHRNA4 | |
| SCHEMBL4413069 | 0.74 | HSD11B1 (0.70) | HSD11B1ALDH1A1KMT2AALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707985-A | Naphthyl-, quinolyl- and isoquinolyl- sulfonamide derivatives as cell adhesion modulators | TANABE SEIYAKU CO. LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| WO-1996040641-A1 | SULFONAMIDE DERIVATIVES AS CELL ADHESION MODULATORS | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-19 | — | — | WO | disclosed |