Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | NPY1R | P25929 | 1/20 | 0.63 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685227 | 0.95 | ALDH1A1 (0.66) | ALDH1A1NPY1RNPY5RLMNAGAA | |
| SCHEMBL9942078 | 0.94 | NPY1R (0.67) | ALDH1A1NPY1RNPY5RLMNAGAA | |
| SCHEMBL3687222 | 0.90 | ALDH1A1 (0.65) | ALDH1A1NPY1RNPY5RLMNAGAA | |
| SCHEMBL10194532 | 0.84 | ALDH1A1 (0.68) | ALDH1A1NPY1RNPY5RLMNAGAA | |
| SCHEMBL6791530 | 0.84 | ALDH1A1 (0.68) | ALDH1A1NPY1RNPY5RLMNAGAA | |
| SCHEMBL3687956 | 0.83 | L3MBTL1 (0.66) | ALDH1A1NPY1RNPY5RLMNAGAA | |
| SCHEMBL25759741 | 0.83 | ALDH1A1 (0.66) | ALDH1A1NPY1RNPY5RLMNAGAA | |
| SCHEMBL30390387 | 0.83 | ALDH1A1 (0.66) | ALDH1A1NPY1RNPY5RLMNAGAA | |
| SCHEMBL1928807 | 0.83 | CYP1A2 (0.67) | ALDH1A1NPY1RNPY5RLMNAGAA | |
| SCHEMBL8330125 | 0.83 | ALDH1A1 (0.52) | ALDH1A1NPY1RNPY5RLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12366579-B2 | Sulfur-heterocycle exchange chemistry and uses thereof | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2025-07-22 | — | — | US | disclosed |
| US-20230125270-A1 | RADIATION SENSITIVE COMPOSITION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2023-04-27 | — | — | US | disclosed |
| US-20220214355-A1 | SULFUR-HETEROCYCLE EXCHANGE CHEMISTRY AND USES THEREOF | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2022-07-07 | — | — | US | disclosed |
| US-20220214355-A1 | SULFUR-HETEROCYCLE EXCHANGE CHEMISTRY AND USES THEREOF | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2022-07-07 | — | — | US | disclosed |
| CN-113853372-A | Thio-heterocyclic exchange chemistry and uses thereof | 弗吉尼亚大学专利基金委员会 | 2021-12-28 | — | — | CN | disclosed |
| EP-3924348-A2 | SULFUR-HETEROCYCLE EXCHANGE CHEMISTRY AND USES THEREOF | University of Virginia Patent Foundation (US) | 2021-12-22 | — | — | EP | disclosed |
| WO-2020214336-A9 | SULFUR-HETEROCYCLE EXCHANGE CHEMISTRY AND USES THEREOF | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2020-11-19 | — | — | WO | disclosed |
| WO-2020214336-A2 | SULFUR-HETEROCYCLE EXCHANGE CHEMISTRY AND USES THEREOF | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2020-10-22 | — | — | WO | disclosed |
| US-20180181000-A1 | RADIATION SENSITIVE COMPOSITION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-06-28 | — | — | US | disclosed |
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| EP-1597248-B1 | SULFONAMIDE DERIVATIVES AS PPAR MODULATORS | LILLY CO ELI (US) | 2007-12-26 | — | — | EP | disclosed |
| US-20060217433-A1 | Sulfonamide derivatives as ppar modulators | ELI LILLY AND COMPANY (US) | 2006-09-28 | — | — | US | disclosed |
| CN-1751037-A | Sulfonamide derivatives as PPAR modulators | LILLY CO ELI (US) | 2006-03-22 | — | — | CN | disclosed |
| EP-1597248-A2 | SULFONAMIDE DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004073606-A2 | SULFONAMIDE DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-09-02 | — | — | WO | disclosed |
| US-6541276-B2 | Nucleophilic reaction of alkoxyamine | VERSICOR, INC. | 2003-04-01 | — | — | US | disclosed |
| US-6448058-B1 | METHOD OF INHIBITING A PEPTIDE DEFORMYLASE, THE METHOD COMPRISING CONTACTING THE PEPTIDE DEFORMYLASE WITH ONE OR MORE COMPOUNDS OF THE INVENTION | VERSICOR, INC. | 2002-09-10 | — | — | US | disclosed |
| US-20010053555-A1 | METHODS FOR SOLID-PHASE SYNTHESIS OF HYDROXYLAMINE COMPOUNDS AND DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | VERSICOR, INC. | 2001-12-20 | — | — | US | disclosed |
| US-6281245-B1 | ADMINISTERING DEFORMYLASE INHIBITOR | VERSICOR, INC. | 2001-08-28 | — | — | US | disclosed |
| WO-1999057097-A2 | METHODS FOR SOLID-PHASE SYNTHESIS OF HYDROXYLAMINE COMPOUNDS AND DERIVATIVES, AND COMBINATORIAL LIBRARIES THEREOF | VERSICOR, INC. (US) | 1999-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220214355-A1 | SULFUR-HETEROCYCLE EXCHANGE CHEMISTRY AND USES THEREOF | TST, TPST2, SRMS | ALDH1A1 3058/4885NPY1R 2848/4885NPY5R 3356/4885 |
| US-20060217433-A1 | Sulfonamide derivatives as ppar modulators | PPARD, PPARA, PPARG | ALDH1A1 1050/4885NPY1R 495/4885NPY5R 567/4885 |
| US-12366579-B2 | Sulfur-heterocycle exchange chemistry and uses thereof | TST, TPST2, SRMS | ALDH1A1 3058/4885NPY1R 2848/4885NPY5R 3356/4885 |
| US-20010053555-A1 | METHODS FOR SOLID-PHASE SYNTHESIS OF HYDROXYLAMINE COMPOUNDS AND DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | HNMT, HAAO, HPSE | ALDH1A1 1020/4885NPY1R 4175/4885NPY5R 4074/4885 |
| US-20180181000-A1 | RADIATION SENSITIVE COMPOSITION | RER1, RAD1, RAD51 | ALDH1A1 1670/4885NPY1R 1936/4885NPY5R 3536/4885 |
| US-20230125270-A1 | RADIATION SENSITIVE COMPOSITION | XRCC6, RAD50, XRCC5 | ALDH1A1 1388/4885NPY1R 2609/4885NPY5R 2007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.