Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8379922 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TSHRSLC6A3LMNASMN1; SMN2 | |
| SCHEMBL29116901 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TSHRSLC6A3SLC6A4SMN1; SMN2 | |
| SCHEMBL29346885 | 0.80 | MRGPRX4 (0.42) | ALDH1A1TSHRSLC6A3SLC6A4MRGPRX4 | |
| SCHEMBL2254189 | 0.78 | KAT6A (0.54) | ALDH1A1TSHRSLC6A3SLC6A4LMNA | |
| SCHEMBL1401560 | 0.76 | TSHR (0.57) | ALDH1A1TSHRSLC6A3SLC6A4LMNA | |
| SCHEMBL31474146 | 0.75 | SOS1 (0.36) | ALDH1A1TSHRSLC6A3SLC6A4MRGPRX4 | |
| SCHEMBL16961479 | 0.73 | LMNA (0.50) | ALDH1A1TSHRSLC6A3SLC6A4LMNA | |
| SCHEMBL2611566 | 0.73 | LMNA (0.50) | ALDH1A1TSHRSLC6A3SLC6A4LMNA | |
| SCHEMBL19335482 | 0.73 | LMNA (0.45) | ALDH1A1LMNASMN1; SMN2CYP2C19GPR174 | |
| SCHEMBL31474131 | 0.72 | PKM (0.38) | ALDH1A1TSHRSMN1; SMN2HSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025061148-A1 | HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2025-03-27 | — | — | WO | disclosed |