Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 16/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BPTF | Q12830 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21963366 | 1.00 | ACHE (0.42) | ACHEMEN1MAPK1KMT2ABPTF | |
| SCHEMBL24978430 | 0.82 | CYP2C19 (0.48) | ACHEMEN1MAPK1KMT2ABPTF | |
| SCHEMBL22020717 | 0.80 | NOS3 (0.50) | ACHEMEN1MAPK1KMT2ABPTF | |
| SCHEMBL28617032 | 0.75 | KDM4E (0.40) | ACHEMEN1MAPK1KMT2ABPTF | |
| SCHEMBL21963370 | 0.75 | ACHE (0.39) | ACHEMEN1MAPK1KMT2ABPTF | |
| SCHEMBL30162186 | 0.75 | ACHE (0.39) | ACHEMEN1MAPK1KMT2ABPTF | |
| SCHEMBL28625362 | 0.72 | ALDH1A1 (0.36) | ACHEMEN1KMT2AGRIN1GRIN2A | |
| SCHEMBL21963078 | 0.72 | NOS3 (0.53) | ACHEMEN1MAPK1KMT2ABPTF | |
| SCHEMBL31475655 | 0.72 | NOS3 (0.53) | ACHEMEN1MAPK1KMT2ABPTF | |
| SCHEMBL31475651 | 0.71 | ACHE (0.42) | ACHEMEN1MAPK1KMT2ABPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166065-B | Compounds and compositions for treating disorders associated with NLRP activity | 诺华股份有限公司 | 2025-04-15 | — | — | CN | disclosed |