Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31476211 | 0.84 | HPGD (0.31) | HCAR3HPGDHCAR2 | |
| SCHEMBL24569481 | 0.83 | HCAR3 (0.40) | L3MBTL1KDM4ENPC1HCAR3HPGD | |
| SCHEMBL31475934 | 0.81 | L3MBTL1 (0.34) | L3MBTL1KDM4ENPC1HCAR3EGFR | |
| SCHEMBL31475900 | 0.80 | HCAR3 (0.43) | L3MBTL1KDM4ENPC1HCAR3MAPT | |
| SCHEMBL29888093 | 0.80 | KDM4E (0.35) | L3MBTL1KDM4ENPC1HCAR3EGFR | |
| SCHEMBL31475721 | 0.79 | FGFR1 (0.41) | KDM4EHCAR3HPGDEGFRERBB2 | |
| SCHEMBL31257435 | 0.75 | L3MBTL1 (0.42) | L3MBTL1KDM4ENPC1HCAR3HPGD | |
| SCHEMBL1191996 | 0.73 | KMT2A (0.46) | KDM4EHPGDEGFRERBB2ALDH1A1 | |
| SCHEMBL24569522 | 0.72 | HCAR3 (0.39) | L3MBTL1KDM4ENPC1HCAR3HPGD | |
| SCHEMBL2992329 | 0.71 | ALDH1A1 (0.52) | KDM4ENPC1HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129078-A1 | ERBB2 INHIBITORS | COGENT BIOSCIENCES, INC. | 2025-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129078-A1 | ERBB2 INHIBITORS | ERBB2, ERBB3, EGFR | L3MBTL1 475/4885KDM4E 1834/4885NPC1 2944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.