Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 11/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1601639 | 0.85 | NOS1 (0.53) | NOS1ALDH1A1AVPR1AGPR6 | |
| SCHEMBL3663893 | 0.75 | AVPR1A (0.56) | GAAALDH1A1AVPR1AGPR6 | |
| SCHEMBL29941296 | 0.75 | AVPR1A (0.56) | GAAALDH1A1AVPR1AGPR6 | |
| SCHEMBL29171392 | 0.74 | NNMT (0.39) | NOS1GAAALDH1A1GPR6 | |
| SCHEMBL288069 | 0.73 | AKT1 (0.44) | ALDH1A1MYCHTR2C | |
| SCHEMBL517896 | 0.73 | HTR2A (0.42) | ALDH1A1ALOX5HTR2AHTR2CSLC6A4 | |
| SCHEMBL17475922 | 0.72 | IDH1 (0.41) | IDH1 | |
| SCHEMBL725593 | 0.72 | IDH1 (0.40) | IDH1 | |
| SCHEMBL31492896 | 0.71 | GAA (0.43) | GAAALDH1A1AVPR1A | |
| SCHEMBL27742432 | 0.71 | LMNA (0.43) | ALDH1A1MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085554-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025085564-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |