Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 14/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725393 | 0.80 | MAPK1 (0.67) | IDH1MAPK1 | |
| SCHEMBL6633559 | 0.77 | FNTA (0.53) | — | |
| SCHEMBL30895899 | 0.77 | FNTA (0.53) | — | |
| SCHEMBL2818152 | 0.76 | MAPK1 (0.63) | MAPK1L3MBTL1 | |
| SCHEMBL4079865 | 0.75 | ABHD6 (0.38) | MAPK1L3MBTL1BRS3 | |
| SCHEMBL28029173 | 0.75 | RIPK1 (0.49) | — | |
| SCHEMBL30314393 | 0.75 | RIPK1 (0.49) | — | |
| SCHEMBL8203594 | 0.72 | DPP8 (0.55) | — | |
| SCHEMBL29992618 | 0.72 | DPP8 (0.55) | — | |
| SCHEMBL31477451 | 0.72 | NOS1 (0.39) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2579863-A2 | COMPOUNDS FOR TREATMENT OF BOVINE MASTITIS | Affinium Pharmaceuticals, Inc. (CA) | 2013-04-17 | — | — | EP | disclosed |
| WO-2011156811-A2 | COMPOUNDS FOR TREATMENT OF BOVINE MASTITIS | AFFINIUM PHARMACEUTICALS, INC. (CA) | 2011-12-15 | — | — | WO | disclosed |