Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3147805 | 0.87 | LMNA (0.73) | LMNATHRB | |
| SCHEMBL1229104 | 0.81 | — | — | |
| SCHEMBL9459 | 0.79 | — | — | |
| SCHEMBL2094168 | 0.79 | LMNA (1.00) | LMNATHRB | |
| SCHEMBL8909577 | 0.79 | — | — | |
| SCHEMBL6551991 | 0.77 | LMNA (0.36) | LMNA | |
| SCHEMBL2416296 | 0.77 | LMNA (0.44) | LMNA | |
| SCHEMBL5105333 | 0.76 | — | — | |
| SCHEMBL3453066 | 0.76 | — | — | |
| SCHEMBL9518993 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088536-A | ALKYLATING LITHIUM CYCLOPENTADIENE, OXYGENATING TO PRODUCE HYDROXYCLYCLOPENTENONES, SEPARATION, MULTISTAGE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1978-05-09 | — | — | US | claimed |
| EP-1169467-B1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDIN PRECURSORS | CHIROTECH TECHNOLOGY LTD (GB) | 2010-02-17 | — | — | EP | disclosed |
| US-20040195108-A1 | Method of producing oxocylohexyl or oxocyclohexylene derivatives | BOTZEM JORG (DE) | 2004-10-07 | — | — | US | disclosed |
| EP-1169467-A1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDIN PRECURSORS | Chirotech Technology Limited (GB) | 2002-01-09 | — | — | EP | disclosed |
| US-20010009770-A1 | Process for the preparation of prostaglandin precursors | FOX MARTIN EDWARD (GB) | 2001-07-26 | — | — | US | disclosed |
| US-6214611-B1 | PREPARATION OF A PROPARGYLIC ALCOHOL ENRICHED IN (R)-ENANTIOMER BY ESTERIFICATION OF RACEMIC ALCOHOL USING ACYL DONOR AND ENZYME, REMOVAL OF UNTREATED (S)-ALCOHOL, AND ENANTIOSELECTIVE HYDROLYSIS OF (R)-ESTER USING SECOND ENZYME | CHIROTECH TECHNOLOGY LIMITED (GB) | 2001-04-10 | — | — | US | disclosed |
| WO-2000061777-A1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDIN PRECURSORS | CHIROTECH TECHNOLOGY LIMITED (GB) | 2000-10-19 | — | — | WO | disclosed |
| EP-0043479-A1 | Novel cyclopentenone derivatives and methods for the preparation of the novel compounds | AMERICAN CYANAMID COMPANY (US) | 1982-01-13 | — | — | EP | disclosed |
| EP-0013107-A1 | 16-Hydroxy-16-vinyl (or cyclopropyl)-prostan-1-ols and pharmaceutical compositions containing the same | AMERICAN CYANAMID COMPANY (US) | 1980-07-09 | — | — | EP | disclosed |
| US-4206151-A | BRONCHODILATOR, ANTISECRETORY, HYPOTENSIVE | AMERICAN CYANAMID COMPANY (US) | 1980-06-03 | — | — | US | disclosed |
| US-4142056-A | MULTISTAGE PROCESS FOR PREPARING 2-(6'-CARBOMETHOXYHEXYL)-2-CYCLOPENTEN-1-ONE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1979-02-27 | — | — | US | disclosed |
| US-4088536-A | ALKYLATING LITHIUM CYCLOPENTADIENE, OXYGENATING TO PRODUCE HYDROXYCLYCLOPENTENONES, SEPARATION, MULTISTAGE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1978-05-09 | — | — | US | disclosed |
| US-4031129-A | LITHIUM CYCLOPENTADIENE, ETHYL-7-BROMOHEPTANOATE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1977-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010009770-A1 | Process for the preparation of prostaglandin precursors | ADH1A, ADH1C, ADH5 | LMNA 2426/4885THRB 1937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.