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Sugi Predict / Compounds / SCHEMBL31479282

SCHEMBL31479282

SCHEMBL31479282

CCN(C(=O)c1cc(F)ccc1-c1cc(N2CCN(C(=O)[C@H]3C4CCC(CC4)N3C(=O)OC(C)(C)C)CC2)cn2c(C)nc(Cl)c12)C(C)C

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ PREP P48147 4/20 0.38
▸ MAPT P10636 4/20 0.34
▸ P2RX7 Q99572 1/20 0.33
▸ MC4R P32245 1/20 0.33
▸ ENPP2 Q13822 1/20 0.32
▸ GPR119 Q8TDV5 4/20 0.31
▸ TP53 P04637 3/20 0.31
▸ LMNA P02545 2/20 0.31
▸ RET P07949 1/20 0.31
▸ THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31479380 0.90 PREP (0.38) PREPMAPTMC4RENPP2GPR119
SCHEMBL31478999 0.89 PREP (0.40) PREPMAPTGPR119
SCHEMBL31479366 0.88 ENPP2 (0.39) MAPTP2RX7ENPP2GPR119
SCHEMBL31479706 0.87 PREP (0.38) PREPMAPTGPR119TP53LMNA
SCHEMBL31478971 0.87 PREP (0.37) PREPMAPTENPP2GPR119LMNA
SCHEMBL31479454 0.85 PREP (0.38) PREPMAPTMC4RGPR119TP53
SCHEMBL31479318 0.84 PREP (0.37) PREPGPR119
SCHEMBL31479463 0.83 MEN1 (0.39) MAPT
SCHEMBL31479050 0.83 PREP (0.41) PREPMAPTGPR119
SCHEMBL31479368 0.79 HCRTR1 (0.34) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067111-A1 MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION 苏州必扬医药科技有限公司 2025-04-03 — — WO disclosed