Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31480601 | 0.91 | NISCH (0.35) | NISCHXIAPBIRC2MAPKAPK2CREBBP | |
| SCHEMBL31480395 | 0.80 | NISCH (0.34) | NISCHXIAPBIRC2MAPKAPK2CREBBP | |
| SCHEMBL31480400 | 0.79 | KDM4E (0.41) | NISCHXIAPBIRC2KDM4ERAB9A | |
| SCHEMBL31480243 | 0.79 | KDM4E (0.43) | NISCHXIAPBIRC2KDM4ERAB9A | |
| SCHEMBL31480262 | 0.78 | ALDH1A1 (0.38) | NISCHMAPKAPK2CREBBPKDM4ERAB9A | |
| SCHEMBL16400464 | 0.74 | NPC1 (0.45) | KDM4ERAB9AALDH1A1NPC1MAPT | |
| SCHEMBL31480286 | 0.72 | ALDH1A1 (0.36) | NISCHMAPKAPK2CREBBPKDM4ERAB9A | |
| SCHEMBL31480318 | 0.71 | MAPK1 (0.33) | — | |
| SCHEMBL31480357 | 0.70 | KDM4E (0.51) | XIAPBIRC2KDM4ERAB9AALDH1A1 | |
| SCHEMBL31480080 | 0.69 | KMT2A (0.36) | MAPKAPK2CREBBPKDM4ERAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054361-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |