Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31480400 | 0.98 | KDM4E (0.41) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL31480395 | 0.91 | NISCH (0.34) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL31480601 | 0.89 | NISCH (0.35) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL31480447 | 0.80 | MAPT (0.33) | KDM4ERAB9ANPSR1ALDH1A1LMNA | |
| SCHEMBL31480436 | 0.80 | VCAM1 (0.42) | KDM4ESMN1; SMN2NPSR1ALDH1A1LMNA | |
| SCHEMBL31480467 | 0.80 | ALDH1A1 (0.35) | KDM4ENPSR1ALDH1A1LMNAALOX15 | |
| SCHEMBL31480315 | 0.79 | NISCH (0.37) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL31480357 | 0.78 | KDM4E (0.51) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL31480606 | 0.78 | CRBN (0.33) | — | |
| SCHEMBL25318693 | 0.78 | NPC1 (0.40) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054361-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |