Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31480590 | 0.85 | HPGD (0.42) | VCAM1HPGDESRRAKMT2AMEN1 | |
| SCHEMBL31480289 | 0.83 | VCAM1 (0.46) | VCAM1HPGDESRRAKMT2AMEN1 | |
| SCHEMBL31480447 | 0.80 | MAPT (0.33) | HPGDKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL31480467 | 0.80 | ALDH1A1 (0.35) | HPGDKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL31480395 | 0.80 | NISCH (0.34) | HPGDKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL31480243 | 0.80 | KDM4E (0.43) | HPGDKMT2AALDH1A1NPSR1MAPT | |
| SCHEMBL31480400 | 0.80 | KDM4E (0.41) | HPGDKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL25318693 | 0.79 | NPC1 (0.40) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL31140806 | 0.79 | NPC1 (0.40) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL25901195 | 0.79 | NPC1 (0.40) | HPGDKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054361-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |