Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1953722 | 0.85 | MTNR1A (0.46) | TSHRMTNR1AMTNR1BSMN1; SMN2NPC1 | |
| SCHEMBL30638160 | 0.84 | MTNR1A (0.61) | TSHRMTNR1AMTNR1BSMN1; SMN2NPC1 | |
| SCHEMBL4687910 | 0.78 | TSHR (0.46) | TSHRSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL29420339 | 0.78 | CA12 (0.51) | TSHRKDM4EL3MBTL1POLB | |
| SCHEMBL15756423 | 0.78 | CA12 (0.51) | TSHRKDM4EL3MBTL1POLB | |
| SCHEMBL5116233 | 0.77 | POLB (0.48) | TSHRMTNR1AMTNR1BSMN1; SMN2NPC1 | |
| SCHEMBL5984317 | 0.77 | HTR1A (0.41) | TSHRMTNR1AMTNR1BSMN1; SMN2NPC1 | |
| SCHEMBL19463672 | 0.77 | KMT2A (0.60) | SMN1; SMN2NPC1RAB9AHPGDKMT2A | |
| SCHEMBL10686596 | 0.77 | SMN1; SMN2 (0.49) | TSHRMTNR1ASMN1; SMN2HPGDKMT2A | |
| SCHEMBL3829038 | 0.77 | LMNA (0.49) | TSHRSMN1; SMN2NPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119841829-A | Compounds for the treatment of PI3K gamma mediated diseases and uses thereof | 中国科学院合肥物质科学研究院 | 2025-04-18 | — | — | CN | disclosed |