SCHEMBL31484571

SCHEMBL31484571

C=Cc1ccc(CO)cc1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.40
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
EGFR P00533 1/20 0.35
SHBG P04278 1/20 0.33
PDCD1 Q15116 3/20 0.33
CD274 Q9NZQ7 3/20 0.33
APP P05067 2/20 0.33
S1PR4 O95977 1/20 0.32
ILK Q13418 1/20 0.32
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
S1PR1 P21453 1/20 0.31
MAOA P21397 1/20 0.31
DYRK1A Q13627 1/20 0.31
DHFR P00374 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1264062 0.82 TRPA1 (0.39) HSD17B10ESR1ESR2PTGS1PTGS2
SCHEMBL5383549 0.81 EGFR (0.42) HSD17B10ESR1ESR2EGFRAPP
SCHEMBL30216932 0.80 ALDH1A1 (0.43) HSD17B10ESR1ESR2EGFRS1PR4
SCHEMBL29467223 0.80 KDM4E (0.36) ESR1ESR2
SCHEMBL809404 0.80 KDM4E (0.36) ESR1ESR2
SCHEMBL17892818 0.80 ALDH1A1 (0.47) PTGS1LMNAMAPT
SCHEMBL9156124 0.80 HRH3 (0.34) ESR1ESR2
SCHEMBL13177068 0.80 ALDH1A1 (0.43) HSD17B10ESR1ESR2EGFRS1PR4
SCHEMBL9915295 0.79 PTGS1 (0.33) ESR1ESR2PDCD1CD274PTGS1
SCHEMBL31670525 0.78 SKP2 (0.42) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775230-A Preparation method and application of tetrahydrofuran cyclostyrenes compound 中国石油化工股份有限公司 2025-04-08 CN disclosed