Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | ESRRB | O95718 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESRRA | P11474 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883945 | 0.83 | EGFR (0.56) | EGFRHSD17B10RECQLXDHTSHR | |
| SCHEMBL17012159 | 0.81 | ALDH1A1 (0.43) | EGFRRECQLTTRALDH1A1HPGD | |
| SCHEMBL31484571 | 0.81 | HSD17B10 (0.40) | EGFRHSD17B10ESR1ESR2MAPT | |
| SCHEMBL15716290 | 0.81 | EGFR (0.35) | EGFRHSD17B10RECQLXDHTSHR | |
| SCHEMBL20199977 | 0.78 | ALDH1A1 (0.49) | CA2TTRKDM4EMEN1ALDH1A1 | |
| SCHEMBL3972895 | 0.77 | TRPA1 (0.41) | EGFRHSD17B10TSHRKDM4EMEN1 | |
| SCHEMBL8345912 | 0.75 | NPC1 (0.43) | HSD17B10RECQLTSHRKDM4EMEN1 | |
| SCHEMBL1979135 | 0.75 | PLAU (0.38) | EGFRENPP2CA12CA2CA3 | |
| SCHEMBL4590318 | 0.75 | ENPP2 (0.34) | EGFRENPP2CA12CA2CA3 | |
| SCHEMBL927054 | 0.73 | CSNK2A1 (0.41) | EGFRTTRKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273911-B2 | Self-adhesive addition-crosslinking silicone compositions | WACKER CHEMIE AG (DE) | 2007-09-25 | — | — | US | disclosed |
| US-20050042462-A1 | Self-adhesive addition-crosslinking silicone compositions | WACKER-CHEMIE GMBH (DE) | 2005-02-24 | — | — | US | disclosed |