Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31565045 | 0.89 | MAPK14 (0.39) | MAPK14ADORA3 | |
| SCHEMBL31486477 | 0.81 | MCHR1 (0.38) | MAPK14ADORA3 | |
| SCHEMBL31486384 | 0.80 | MAPK14 (0.35) | MAPK14RPS6KB1POLB | |
| SCHEMBL31486436 | 0.80 | F7 (0.34) | RPS6KB1NR3C1 | |
| SCHEMBL31486324 | 0.80 | RAB9A (0.33) | — | |
| SCHEMBL31486452 | 0.76 | RPS6KB1 (0.33) | MAPK14RPS6KB1POLB | |
| SCHEMBL31486469 | 0.75 | MAPK14 (0.40) | MAPK14ADORA3 | |
| SCHEMBL31486546 | 0.74 | RPS6KB1 (0.39) | MAPK14RPS6KB1 | |
| SCHEMBL31486305 | 0.73 | MAPK14 (0.37) | MAPK14 | |
| SCHEMBL31486510 | 0.68 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122225-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2025-04-17 | — | — | US | disclosed |
| WO-2025076476-A2 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2025-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122225-A1 | MASP-2 INHIBITORS AND METHODS OF USE | MASP2, SPINT2, SERPINB1 | MAPK14 2151/4885RPS6KB1 2675/4885ADORA3 4615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.