Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL31486378

Cc1cc(F)cc(CNc2nc(-c3ccnn3C)c3n(c2=O)[C@H](C(=O)NCc2cc4c(s2)CNC4)CC3)c1.O=C(O)C(F)(F)F

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.30
F2 P00734 1/20 0.30
F7 P08709 1/20 0.30
F3 P13726 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL31486312 0.86
SCHEMBL31486516 0.84 TGM2 (0.30)
SCHEMBL31486191 0.81 PREP (0.36) F2F7F3
SCHEMBL31486407 0.80 F7 (0.42) F2F7F3
Trifluoroacetic Acid SCHEMBL31486183 0.72 TPSAB1 (0.39) F2F7F3
Trifluoroacetic Acid SCHEMBL31486462 0.71 TPSAB1 (0.47) F2F7F3
Trifluoroacetic Acid SCHEMBL31486403 0.71 RAD52 (0.33)
Trifluoroacetic Acid SCHEMBL31486424 0.70 RAD52 (0.34) F2
SCHEMBL30929408 0.69 F2 (0.46) F2F7F3
SCHEMBL31486419 0.67 F7 (0.41) F2F7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250122225-A1 MASP-2 INHIBITORS AND METHODS OF USE OMEROS CORPORATION (US) 2025-04-17 US disclosed
WO-2025076476-A2 MASP-2 INHIBITORS AND METHODS OF USE OMEROS CORPORATION (US) 2025-04-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122225-A1 MASP-2 INHIBITORS AND METHODS OF USE MASP2, SPINT2, SERPINB1 TRPA1 4611/4885F2 117/4885F7 1426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.