Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.39 |
| ▸ | PREP | P48147 | 9/20 | 0.35 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31486546 | 0.84 | RPS6KB1 (0.39) | RPS6KB1PREPAURKAJAK2JAK1 | |
| SCHEMBL31486419 | 0.81 | F7 (0.41) | RPS6KB1PREPACE | |
| SCHEMBL31486531 | 0.80 | RPS6KB1 (0.36) | RPS6KB1PREPACE | |
| SCHEMBL31486352 | 0.79 | RPS6KB1 (0.37) | RPS6KB1PREPACE | |
| SCHEMBL6073838 | 0.79 | ALDH1A1 (0.40) | PREPACE | |
| SCHEMBL30929451 | 0.78 | F2 (0.44) | RPS6KB1PREPRIPK1 | |
| SCHEMBL31486338 | 0.78 | PREP (0.36) | RPS6KB1PREPACE | |
| SCHEMBL31486244 | 0.77 | MET (0.37) | RPS6KB1PREPACE | |
| SCHEMBL31486384 | 0.76 | MAPK14 (0.35) | RPS6KB1PREPACEMAPK14 | |
| SCHEMBL31486440 | 0.75 | PREP (0.36) | RPS6KB1PREPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076476-A2 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2025-04-10 | — | — | WO | disclosed |