Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31487322 | 0.89 | PDE5A (0.48) | PDE5AAPPCDK1ESR1ALDH1A1 | |
| SCHEMBL30948905 | 0.80 | PDE5A (0.51) | PDE5AAPPCDK1ESR1ALDH1A1 | |
| SCHEMBL30948921 | 0.78 | PDE5A (0.49) | PDE5AAPPCDK1ESR1ALDH1A1 | |
| SCHEMBL30948919 | 0.78 | APP (0.49) | PDE5AAPPHSD17B10CDK1ESR1 | |
| SCHEMBL31487415 | 0.75 | PDE5A (0.46) | PDE5AAPPCDK1ESR1ALDH1A1 | |
| SCHEMBL31487162 | 0.74 | CDK1 (0.46) | PDE5AAPPCDK1ESR1KDM4E | |
| SCHEMBL31487219 | 0.73 | APP (0.44) | PDE5AAPPHSD17B10ALOX15CDK1 | |
| SCHEMBL31487047 | 0.73 | APP (0.44) | PDE5AAPPALOX15CDK1ESR1 | |
| SCHEMBL31487285 | 0.73 | MAPT (0.44) | PDE5AAPPCDK1ALDH1A1KMT2A | |
| SCHEMBL31487224 | 0.73 | PDE5A (0.49) | PDE5AAPPCDK1ESR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025074096-A1 | P97 (VCP) ATPASE INHIBITORS | Turbine Simulated Cell Technologies Ltd (GB) | 2025-04-10 | — | — | WO | disclosed |