Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30948905 | 0.81 | PDE5A (0.51) | MAPTKDM4EPDE5AAPPLMNA | |
| SCHEMBL30948919 | 0.79 | APP (0.49) | MAPTKDM4EPDE5AAPPLMNA | |
| SCHEMBL30948921 | 0.79 | PDE5A (0.49) | MAPTKDM4EPDE5AAPPLMNA | |
| SCHEMBL31487219 | 0.79 | APP (0.44) | KDM4EPDE5AAPPHTTLMNA | |
| SCHEMBL31487415 | 0.78 | PDE5A (0.46) | MAPTKDM4EPDE5AAPPHPGD | |
| SCHEMBL31487322 | 0.78 | PDE5A (0.48) | MAPTPDE5AAPPHPGDALDH1A1 | |
| SCHEMBL31487162 | 0.75 | CDK1 (0.46) | MAPTKDM4EPDE5AAPPCDK1 | |
| SCHEMBL31487263 | 0.74 | F2 (0.45) | KDM4EPDE5AAPPHPGDALDH1A1 | |
| SCHEMBL31487047 | 0.74 | APP (0.44) | MAPTKDM4EPDE5AAPPLMNA | |
| SCHEMBL25178502 | 0.73 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025074096-A1 | P97 (VCP) ATPASE INHIBITORS | Turbine Simulated Cell Technologies Ltd (GB) | 2025-04-10 | — | — | WO | disclosed |