Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3145602 | 0.89 | CYP3A4 (0.40) | MAPTGAATDP1NPC1RAB9A | |
| SCHEMBL7982172 | 0.89 | MAPT (0.47) | ADRA2BADRA2CMAPTGAATDP1 | |
| SCHEMBL28170208 | 0.86 | MAPT (0.55) | ADRA2BADRA2CMAPTGAATDP1 | |
| SCHEMBL3148744 | 0.85 | MEN1 (0.48) | MAPTGAANPC1RAB9AMEN1 | |
| SCHEMBL13813554 | 0.84 | ADRA2B (0.46) | ADRA2BADRA2CMAPTGAAP2RX7 | |
| SCHEMBL14321012 | 0.83 | CYP3A4 (0.42) | MAPTGAATDP1NPC1RAB9A | |
| SCHEMBL8418766 | 0.80 | FABP4 (0.38) | ADRA2BADRA2CMAPTGAATDP1 | |
| SCHEMBL14320957 | 0.80 | LIPG (0.51) | MAPTSMN1; SMN2HSD17B10LMNA | |
| SCHEMBL11380769 | 0.80 | LIPG (0.51) | MAPTSMN1; SMN2HSD17B10LMNA | |
| SCHEMBL8418765 | 0.79 | SMN1; SMN2 (0.36) | ADRA2BADRA2CMAPTGAAP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642028-B2 | surface layers are a polymeric composition including a resin and a cyclic polymers such as polyethylene terephthalate, acrylic acid-ethylene copolymer, styrene-co-maleic anhydride copolymer; polyhexamethylene adipamide etc. and cyclic poly(bisphenol A carbonate), cyclic poly(bisphenol C carbonate) etc. | XEROX CORPORATION (US) | 2010-01-05 | — | — | US | claimed |
| US-20060210894-A1 | Imaging members | XEROX CORPORATION | 2006-09-21 | — | — | US | claimed |