Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31487405 | 0.87 | OPRL1 (0.36) | THRBOPRM1OPRL1OPRK1HTR1A | |
| SCHEMBL30965709 | 0.80 | CRBN (0.41) | DRD2 | |
| SCHEMBL31487455 | 0.80 | CHRM2 (0.37) | HTR1ADRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL31487472 | 0.79 | ADRA1B (0.37) | HTR1ADRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL31487430 | 0.77 | HTR1A (0.43) | HTR1ADRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL31487740 | 0.76 | ADRA1B (0.38) | OPRM1OPRL1OPRK1HTR1ADRD2 | |
| SCHEMBL31487719 | 0.74 | DRD2 (0.38) | HTR1ADRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL31487439 | 0.71 | HTR6 (0.39) | THRBHTR1ADRD2CDK4CCND1 | |
| SCHEMBL25034798 | 0.70 | DDB1 (0.46) | OPRM1OPRL1OPRK1DRD2OPRD1 | |
| SCHEMBL30965761 | 0.69 | CRBN (0.40) | OPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119790057-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2025-04-08 | — | — | CN | disclosed |