Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.54 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31487843 | 0.83 | RET (0.55) | GPR119RETHPGDS | |
| SCHEMBL31487895 | 0.81 | DDB1 (0.47) | GPR119RETHPGDS | |
| SCHEMBL31487734 | 0.81 | GPR119 (0.52) | GPR119RETHPGDSKDM4EMAPT | |
| SCHEMBL31487760 | 0.81 | GPR119 (0.47) | GPR119RETHPGDSHPGDKDM4E | |
| SCHEMBL31487905 | 0.81 | GPR119 (0.35) | GPR119KDM4EHSD17B10 | |
| SCHEMBL31487766 | 0.80 | GPR119 (0.48) | GPR119RETHPGDSHPGDKDM4E | |
| SCHEMBL31487815 | 0.76 | NR3C1 (0.43) | GPR119RETHPGDSHPGDKDM4E | |
| SCHEMBL31487761 | 0.75 | ACVR1 (0.41) | RET | |
| SCHEMBL31487820 | 0.75 | RET (0.47) | GPR119RETHPGDKDM4EMEN1 | |
| SCHEMBL31487807 | 0.75 | GPR119 (0.44) | GPR119RETHPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025089370-A1 | COMPOUNDS AS CSF1R INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2025-05-01 | — | — | WO | disclosed |