SCHEMBL31487905

SCHEMBL31487905

O=C(OCc1cscn1)N1CCC(c2cnn3cc(-c4cncs4)cnc23)CC1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 1/20 0.35
▸ MMP2 P08253 1/20 0.32
▸ MMP9 P14780 1/20 0.32
▸ CYP3A4 P08684 1/20 0.31
▸ GRM5 P41594 1/20 0.31
▸ GRIN2B Q13224 1/20 0.31
▸ CD38 P28907 1/20 0.31
▸ WNT1 P04628 1/20 0.30
▸ GSK3B P49841 1/20 0.30
▸ DYRK1A Q13627 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30
▸ HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31487877 0.82 MMP2 (0.34) GPR119MMP2MMP9CYP3A4GRM5
SCHEMBL31487735 0.81 GPR119 (0.54) GPR119KDM4EHSD17B10
SCHEMBL31487850 0.80 MMP2 (0.35) GPR119MMP2MMP9CYP3A4GRIN2B
SCHEMBL31488044 0.80 RORC (0.36) GPR119MMP2MMP9GRIN2BKDM4E
SCHEMBL31487992 0.78 KMT2A (0.34) GPR119MMP2MMP9GRM5
SCHEMBL31487773 0.77 TLR9 (0.35) MMP2MMP9
SCHEMBL31487777 0.74 JAK2 (0.38) GPR119KDM4EHSD17B10
SCHEMBL31487756 0.72 ROCK2 (0.38) GPR119MMP2MMP9GRM5GRIN2B
SCHEMBL31487761 0.71 ACVR1 (0.41) —
SCHEMBL31487805 0.71 ALDH1A1 (0.38) MMP2MMP9GRM5KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025089370-A1 COMPOUNDS AS CSF1R INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2025-05-01 — — WO disclosed
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