SCHEMBL31487901

SCHEMBL31487901

CC(C)(C)OC(=O)N1CCC(c2cnn3cc(OC4CC4)ccc23)CC1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 10/20 0.52
▸ HTT P42858 1/20 0.44
▸ MAPT P10636 1/20 0.44
▸ NPBWR1 P48145 1/20 0.43
▸ MCHR1 Q99705 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ USP2 O75604 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31487842 0.94 GPR119 (0.48) GPR119HTTNPBWR1MCHR1
SCHEMBL31487739 0.93 GPR119 (0.48) GPR119HTTMAPTNPBWR1MCHR1
SCHEMBL31487750 0.89 ALDH1A1 (0.53) GPR119HTTMAPTALDH1A1MEN1
SCHEMBL31487824 0.87 GPR119 (0.49) GPR119HTT
SCHEMBL31487545 0.86 MEN1 (0.45) GPR119HTTMAPTALDH1A1MEN1
SCHEMBL31488149 0.85 MEN1 (0.54) MAPTALDH1A1MEN1USP2HPGD
SCHEMBL31487885 0.85 GPR119 (0.46) GPR119HTTMAPTALDH1A1MEN1
SCHEMBL31488033 0.85 RET (0.49) GPR119HTTMAPTALDH1A1MEN1
SCHEMBL31487825 0.85 TP53 (0.45) GPR119HTTMAPTALDH1A1MEN1
SCHEMBL31488117 0.84 MEN1 (0.44) GPR119HTTMAPTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025089370-A1 COMPOUNDS AS CSF1R INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2025-05-01 — — WO disclosed
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