SCHEMBL31487739

SCHEMBL31487739

CC(C)(C)OC(=O)N1CCC(c2cnn3cc(OC4CCNCC4)ccc23)CC1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 6/20 0.48
▸ HTT P42858 1/20 0.43
▸ CHEK2 O96017 1/20 0.42
▸ HPGDS O60760 1/20 0.42
▸ MAPT P10636 2/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ THRB P10828 1/20 0.41
▸ DDB1 Q16531 1/20 0.41
▸ CRBN Q96SW2 1/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ NPBWR1 P48145 1/20 0.41
▸ MCHR1 Q99705 1/20 0.41
▸ USP2 O75604 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31487901 0.93 GPR119 (0.52) GPR119HTTMAPTMEN1KMT2A
SCHEMBL31487842 0.89 GPR119 (0.48) GPR119HTTCHEK2THRBNPBWR1
SCHEMBL31487750 0.85 ALDH1A1 (0.53) GPR119HTTMAPTKDM4EMEN1
SCHEMBL31487824 0.83 GPR119 (0.49) GPR119HTTTHRB
SCHEMBL31487545 0.81 MEN1 (0.45) GPR119HTTMAPTKDM4ETHRB
SCHEMBL31488149 0.81 MEN1 (0.54) MAPTTHRBMEN1KMT2AUSP2
SCHEMBL31487825 0.80 TP53 (0.45) GPR119HTTMAPTKDM4EMEN1
SCHEMBL31488033 0.80 RET (0.49) GPR119HTTMAPTKDM4EMEN1
SCHEMBL31487835 0.80 GPR119 (0.53) GPR119MEN1KMT2AUSP2HPGD
SCHEMBL31487833 0.80 KMT2A (0.48) GPR119HTTHPGDSMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025089370-A1 COMPOUNDS AS CSF1R INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2025-05-01 — — WO disclosed
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