SCHEMBL31488149

SCHEMBL31488149

CC(C)(C)OC(=O)N1CCC(c2cnn3cc(Cl)ccc23)CC1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.54
▸ KMT2A Q03164 3/20 0.54
▸ NPSR1 Q6W5P4 2/20 0.54
▸ USP2 O75604 1/20 0.54
▸ HPGD P15428 1/20 0.54
▸ HSD17B10 Q99714 1/20 0.54
▸ LMNA P02545 4/20 0.51
▸ ALDH1A1 P00352 1/20 0.50
▸ GAA P10253 1/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ TP53 P04637 4/20 0.47
▸ STS P08842 1/20 0.47
▸ MAPT P10636 3/20 0.47
▸ CNR1 P21554 2/20 0.47
▸ THRB P10828 1/20 0.46
▸ POLB P06746 1/20 0.46
▸ RXFP1 Q9HBX9 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31487545 0.88 MEN1 (0.45) MEN1KMT2ANPSR1USP2HPGD
SCHEMBL31487750 0.87 ALDH1A1 (0.53) MEN1KMT2AHPGDHSD17B10LMNA
SCHEMBL31487833 0.86 KMT2A (0.48) MEN1KMT2ANPSR1USP2HPGD
SCHEMBL31488117 0.86 MEN1 (0.44) MEN1KMT2ANPSR1USP2HPGD
SCHEMBL31487870 0.85 GPR119 (0.48) MEN1KMT2ANPSR1USP2HPGD
SCHEMBL31487901 0.85 GPR119 (0.52) MEN1KMT2ANPSR1USP2HPGD
SCHEMBL31487926 0.84 MAPT (0.50) MEN1KMT2ANPSR1USP2HPGD
SCHEMBL31487835 0.84 GPR119 (0.53) MEN1KMT2ANPSR1USP2HPGD
SCHEMBL31487769 0.83 ALOX5AP (0.44) MEN1KMT2ANPSR1USP2HPGD
SCHEMBL31488038 0.83 RET (0.59) MEN1KMT2AHPGDHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025089370-A1 COMPOUNDS AS CSF1R INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2025-05-01 — — WO disclosed
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