Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489148 | 0.81 | CA12 (0.44) | POLBALDH1A1KDM1AMAOAMAOB | |
| SCHEMBL30407874 | 0.78 | FAAH (0.46) | MAPTALDH1A1RAD51KMT2AKDM4E | |
| SCHEMBL31489034 | 0.77 | RAB9A (0.47) | RAB9ATDP1NPC1ATM | |
| SCHEMBL31489018 | 0.75 | NAMPT (0.55) | — | |
| SCHEMBL31488799 | 0.74 | ALDH1A1 (0.56) | MAPTTP53POLBALDH1A1RAD51 | |
| SCHEMBL30059309 | 0.74 | LMNA (0.49) | POLBALDH1A1KMT2AGAARAB9A | |
| SCHEMBL13878591 | 0.74 | EPHX2 (0.47) | ALDH1A1KMT2AUSP2MEN1HPGD | |
| SCHEMBL38659346 | 0.73 | NPC1 (0.43) | MAPTTP53ALDH1A1MAOAGAA | |
| SCHEMBL28561557 | 0.73 | MAPT (0.57) | MAPTTP53POLBALDH1A1KDM1A | |
| SCHEMBL20564912 | 0.73 | ALDH1A1 (0.49) | MAPTTP53POLBALDH1A1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072437-A1 | HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ALPHINA THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |