Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KPNA2 | P52292 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489390 | 0.80 | JAK1 (0.39) | JAK1NUDT1KDM4EALDH1A1HPGD | |
| SCHEMBL31489241 | 0.74 | PIK3CG (0.40) | NUDT1KDM4EALDH1A1PKMGLA | |
| SCHEMBL2984728 | 0.68 | ALDH1A1 (0.44) | JAK1KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL15579070 | 0.68 | NUDT1 (0.43) | JAK1NUDT1KDM4EALDH1A1HPGD | |
| SCHEMBL7870538 | 0.67 | JAK1 (0.42) | JAK1NUDT1KDM4EALDH1A1HPGD | |
| SCHEMBL30874446 | 0.63 | CA12 (0.32) | SMN1; SMN2CA12CA1CA2CA3 | |
| SCHEMBL20844717 | 0.63 | NUDT1 (0.38) | NUDT1KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL22207511 | 0.62 | ALDH1A1 (0.41) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1907671 | 0.62 | PDE10A (0.34) | PDE10A | |
| SCHEMBL2254006 | 0.62 | NUDT1 (0.57) | NUDT1KDM4EALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |